Manchester City have the advantage of playing 24 hours ahead of Liverpool and the chance to reduce the log leaders’ gap to just one point.
Since losing to Leicester City 1-2 on Boxing Day, City have won eight matches in all competitions, smashing in 35 goals and conceding only two.
City’s hosts Newcastle had a good time on their home ground in their last league match beating Cardiff City 3-0, but lost seven days later at same venue in the FA Cup to Watford.
Arsenal got bundled out of the second cup competition on Friday when Manchester United took advantage of their inconsistent form to triumph at Emirates Stadium in the FA Cup.
The Gunners will face Cardiff City hoping to make amends and be in pursuit of Chelsea for fourth place.
Meanwhile, Manchester United will file out at Old Trafford with their confidence boosted by the results under interim manager Ole Gunnar Solskjær. Eight wins in as many matches under the Norwegian have changed the gloom under Jose Mourinho to optimism. Now the Red Devils can really and truly challenge for Champions League places, being only three points off the cut at the moment.
2018/19 English Premier League (Week 24): Arsenal v Cardiff City, Fulham v Brighton & Hove Albion, Huddersfield Town v Everton, Wolverhampton Wanderers v West Ham United (all 8:45pm); Manchester United v Burnley, Newcastle United v Manchester City (both 9pm)
2018/19 Spanish Copa del Rey (1/4 finals second leg): Valencia v Getafe (first leg Getafe 1-0) (9:30pm)
2018/19 Copa Italia (¼ final): AC Milan v Napoli (8:45pm)
2018/19 French League Cup (Semi-final): EA Guingamp v AS Monaco (9:05pm)